化学经纬
化学经纬

Nickel-Mediated Chan–Lam Coupling

chem有机方法416230

Nickel-Mediated Chan–Lam Coupling 第1张

An efficient use of NiCl2·6H2O, for the cross-coupling of arylboronic acids with various N-nucleophiles, has been demonstrated. The method is practical and offers an alternative to the corresponding Cu-mediated Chan–Lam process for the construction of the C–N bond.

Nickel-Mediated Chan–Lam Coupling 第2张

Org. Lett., 2012, 14 (17), pp 4326–4329
DOI: 10.1021/ol3021836


标签: Chan–Lam

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